Aaron R. Folsom

Professor 路 Osaka University

The University of Osaka

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h-index171
Publications1,270
Last 5y84
English accessEnglish-language information not found on lab site

Research summary

The Multi-Ethnic Study of Atherosclerosis (MESA) reported that coronary-artery calcium measured by computed tomography predicts coronary heart disease events independently of traditional risk factors across white, Black, Hispanic and Chinese American participants, extending earlier findings beyond predominantly white populations [1]. A separate MESA analysis showed that brachial-artery flow-mediated dilation is associated with incident cardiovascular events in adults free of cardiovascular disease, although the predictive value remained modest after adjustment for established risk factors [7]. A pooled prospective analysis of 1.46 million white adults examined Cox regression-based hazard ratios for body-mass index and all-cause mortality, showing an elevated mortality risk at both low and high BMI extremes [2]. Genome-wide association scanning across six independent samples (more than 23,000 participants) from four Caucasian populations identified a 58-kilobase interval on chromosome 9p21, near the CDKN2A and CDKN2B genes, that is consistently associated with coronary heart disease [3]. Within the Atherosclerosis Risk in Communities (ARIC) case-cohort study of 10,275 participants (581 incident diabetes cases versus 572 non-cases), low-grade systemic inflammation was associated with the development of type 2 diabetes [4]. In the Iowa Women's Health Study, dietary antioxidant vitamins were assessed in 34,486 postmenopausal women free of cardiovascular disease, examining whether intake of vitamin E, vitamin C and carotenoids modified the risk of coronary heart disease death [5]. An earlier ARIC analysis evaluated the associations of estrogen and combined estrogen-progestin hormone replacement therapy with plasma lipids, hemostatic factors and other cardiovascular risk factors in postmenopausal women [6].

Recent publications

  1. Coronary Calcium as a Predictor of Coronary Events in Four Racial or Ethnic Groups2008 路 New England Journal of Medicine 路 2938 citationsDOI
  2. Body-Mass Index and Mortality among 1.46 Million White Adults2010 路 New England Journal of Medicine 路 2310 citationsDOI
  3. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease2011 路 Nature Genetics 路 1940 citationsDOI
  4. A Common Allele on Chromosome 9 Associated with Coronary Heart Disease2007 路 Science 路 1573 citationsDOI
  5. Low-Grade Systemic Inflammation and the Development of Type 2 Diabetes2003 路 Diabetes 路 1043 citationsDOI
  6. Dietary Antioxidant Vitamins and Death from Coronary Heart Disease in Postmenopausal Women1996 路 New England Journal of Medicine 路 964 citationsDOI
  7. Association of Hormone-Replacement Therapy with Various Cardiovascular Risk Factors in Postmenopausal Women1993 路 New England Journal of Medicine 路 914 citationsDOI
  8. Carotid Intima-Media Thickness and Presence or Absence of Plaque Improves Prediction of Coronary Heart Disease Risk2010 路 Journal of the American College of Cardiology 路 906 citationsDOI
  9. Predictive Value of Brachial Flow-Mediated Dilation for Incident Cardiovascular Events in a Population-Based Study2009 路 Circulation 路 883 citationsDOI
  10. Deep vein thrombosis and pulmonary embolism in two cohorts: the longitudinal investigation of thromboembolism etiology2004 路 The American Journal of Medicine 路 872 citationsDOI

The lab page does not clearly state student acceptance status. Email the professor directly to confirm.

How to apply

Email Aaron R. Folsom 6-12 months before your application deadline. Read several recent papers and reference specific work in your message. Use our how to email a Japanese professor guide for the proven email structure.

For applications via MEXT scholarship: see our MEXT 2027 complete guide and university-specific University Recommendation track.

External profiles

Profile compiled from public sources (Researchmap, OpenAlex, Osaka University faculty directory). Last refreshed 2026-05. Report incorrect information.

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