Research summary
A 2006 Advanced Materials review of hydrogels in biology and medicine analyzes hydrophilic polymers (natural, biohybrid, and synthetic) as thin films, scaffolds, and nanoparticles, covering crosslinked and uncrosslinked systems and their thermodynamic responses for sensors, microarrays, imaging, and therapeutic delivery [1]. A 2009 Advanced Materials review of hydrogels in regenerative medicine examines structural integrity, controlled drug and protein delivery, and material design constraints inherent in synthesizing hydrogels for tissue engineering [2]. A PNAS review of microscale technologies for tissue engineering surveys 3D microfabricated scaffolds, templates for cell aggregate formation, and the use of microfluidics, surface patterning, and patterned cocultures to regulate the cellular microenvironment in vitro and enable high-throughput cellular assays [3]. The 2013 25th Anniversary Article in Advanced Materials covers rational design of hydrogels with tunable physiochemical properties for 3D tissue-engineering matrices, drug delivery, composite biomaterials, and injectable fillers, and addresses how property tuning modulates cellular function and tissue morphogenesis [4]. A 2017 ACS Nano review of nanomedicine spans drug delivery, vaccines, antibacterial materials, imaging, wearable devices, and high-throughput screening using biological, biomimetic, and hybrid nanomaterials [5]. A 2010 Tissue Engineering Part B review focuses on the porosity and microarchitecture of hydrogel scaffolds, noting that traditional bulk-porosity techniques can be incompatible with direct cell encapsulation and reviewing emerging methods that overcome this constraint [6]. A 2023 ACS Nano technology roadmap for flexible sensors identifies bottlenecks limiting market adoption and discusses sensing performance, sensor-biology interfaces, and manufacturing routes [7]. A Biotechnology and Bioengineering review of nanocomposite hydrogels covers carbon-based, polymeric, ceramic, and metallic nanoparticle integration into hydrogel networks to tailor physical, chemical, electrical, and biological properties [8]. Across the portfolio, hydrogels are treated both as biomimetic extracellular-matrix analogs and as a tunable platform for combining biological, electrical, and mechanical functionality.
Recent publications
- Hydrogels in Biology and Medicine: From Molecular Principles to BionanotechnologyDOI
- Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogelsDOI
- Hydrogels in Regenerative MedicineDOI
- Cell-laden microengineered gelatin methacrylate hydrogelsDOI
- Microscale technologies for tissue engineering and biologyDOI
- 25th Anniversary Article: Rational Design and Applications of Hydrogels in Regenerative MedicineDOI
- Diverse Applications of NanomedicineDOI
- Controlling the Porosity and Microarchitecture of Hydrogels for Tissue EngineeringDOI
- Technology Roadmap for Flexible SensorsDOI
- Nanocomposite hydrogels for biomedical applicationsDOI
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How to apply
Email Ali Khademhosseini 6-12 months before your application deadline. Read several recent papers and reference specific work in your message. Use our how to email a Japanese professor guide for the proven email structure.
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External profiles
- ORCID: https://orcid.org/0000-0002-2692-1524
- OpenAlex: openalex.org
Profile compiled from public sources (Researchmap, OpenAlex, Tohoku University faculty directory). Last refreshed 2026-05. Report incorrect information.