Research summary
Contributions sit within prospective-cohort nutritional epidemiology, drawing on the Nurses' Health Study, the Health Professionals Follow-up Study, and randomized trials. Methodological work validated an expanded 131-item semiquantitative food frequency questionnaire by administering the form by mail twice at one-year intervals to 127 participants from a cohort of 51,529 men, with two one-week diet records and intraclass correlation coefficients ranging from 0.47 (vitamin E without supplements) to 0.80 (vitamin C with supplements) [4]. In 39,910 male health professionals followed for four years, dietary intake of vitamin C, carotene, and vitamin E was related to incident coronary heart disease, framed by the LDL-oxidation hypothesis of atherogenesis [2]. A nested case-control study of 152 cases and 152 controls within the Physicians' Health Study found plasma insulin-like growth factor I (IGF-I) in the highest quartile associated with a 4.3-fold relative risk of prostate cancer independent of baseline PSA [5]. A consensus statement assembled by the American Diabetes Association and American Cancer Society reviewed the association between diabetes and cancer incidence and prognosis, shared risk factors, biologic links, and effects of diabetes treatments on cancer outcomes [3]. A randomized factorial trial tested cholecalciferol (2,000 IU/day) and marine omega-3 fatty acids (1 g/day) against placebo for incident invasive cancer and major cardiovascular events in adults aged >=50 (men) and >=55 (women) [6]. A dose-response meta-analysis of prospective studies synthesized fruit and vegetable intake associations with cardiovascular disease, total cancer, and all-cause mortality, finding positive dose-response relationships [1]. Across these papers the methodological signature is the design and statistical analysis of long-term cohort and randomized data on diet, lifestyle, and biomarkers, with attention to measurement-error and confounding through validated questionnaires and multivariable adjustment.
Recent publications
- A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010DOI
- Global burden of colorectal cancer: emerging trends, risk factors and prevention strategiesDOI
- Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomesDOI
- Fruit and vegetable intake and the risk of cardiovascular disease, total cancer and all-cause mortality—a systematic review and dose-response meta-analysis of prospective studiesDOI
- Vitamin E Consumption and the Risk of Coronary Heart Disease in MenDOI
- Diabetes and CancerDOI
- Reproducibility and Validity of an Expanded Self-Administered Semiquantitative Food Frequency Questionnaire among Male Health ProfessionalsDOI
- Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective StudyDOI
- Global Burden of 5 Major Types of Gastrointestinal CancerDOI
- Vitamin D Supplements and Prevention of Cancer and Cardiovascular DiseaseDOI
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How to apply
Email Edward L. Giovannucci 6-12 months before your application deadline. Read several recent papers and reference specific work in your message. Use our how to email a Japanese professor guide for the proven email structure.
For applications via MEXT scholarship: see our MEXT 2027 complete guide and university-specific University Recommendation track.
External profiles
- ORCID: https://orcid.org/0000-0002-6123-0219
- OpenAlex: openalex.org
Profile compiled from public sources (Researchmap, OpenAlex, The University of Tokyo faculty directory). Last refreshed 2026-05. Report incorrect information.