Research summary
Yeast one-hybrid screening with the dehydration-responsive element (DRE) recovered two cDNAs encoding DRE-binding proteins, DREB1A and DREB2A, from dehydrated and cold-treated Arabidopsis rosette libraries; these EREBP/AP2-domain factors separate the cold and drought signaling branches of DRE-mediated gene induction [1]. Earlier work on the closely linked rd29A/rd29B promoters identified a novel 9-bp cis-acting element (TACCGACAT, the DRE) involved in dehydration, low-temperature and high-salt responsiveness in transgenic Arabidopsis and tobacco [5]. The bHLH factor AtMYC2 and the MYB factor AtMYB2, which bind the rd22 MYC/MYB recognition sites, were shown to act as transcriptional activators in ABA signaling, with overexpressing transgenic plants showing heightened ABA sensitivity [4]. Reviews in Annual Review of Plant Biology and Journal of Experimental Botany synthesized the transcriptional regulatory networks and gene networks underlying drought, cold and high-salinity responses, mapping the cis-elements and transcription factors that confer stress-inducible expression and stress tolerance [2][3]. A full-length cDNA microarray of ~7000 Arabidopsis genes was used to profile drought, cold and high-salinity responses, identifying 277, 53 and 194 genes induced more than fivefold by drought, cold and salt respectively [6].
Recent publications
- Genome sequence of the palaeopolyploid soybeanDOI
- Two Transcription Factors, DREB1 and DREB2, with an EREBP/AP2 DNA Binding Domain Separate Two Cellular Signal Transduction Pathways in Drought- and Low-Temperature-Responsive Gene Expression, Respectively, in ArabidopsisDOI
- TRANSCRIPTIONAL REGULATORY NETWORKS IN CELLULAR RESPONSES AND TOLERANCE TO DEHYDRATION AND COLD STRESSESDOI
- Gene networks involved in drought stress response and toleranceDOI
- The complete nucleotide sequence of the tobacco chloroplast genome: its gene organization and expressionDOI
- Arabidopsis AtMYC2 (bHLH) and AtMYB2 (MYB) Function as Transcriptional Activators in Abscisic Acid SignalingDOI
- Improving plant drought, salt, and freezing tolerance by gene transfer of a single stress-inducible transcription factorDOI
- DNA-Binding Specificity of the ERF/AP2 Domain of Arabidopsis DREBs, Transcription Factors Involved in Dehydration- and Cold-Inducible Gene ExpressionDOI
- A novel cis-acting element in an Arabidopsis gene is involved in responsiveness to drought, low-temperature, or high-salt stress.DOI
- Monitoring the expression profiles of 7000 Arabidopsis genes under drought, cold and high鈥恠alinity stresses using a full鈥恖ength cDNA microarrayDOI
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Email Kazuo Shinozaki 6-12 months before your application deadline. Read several recent papers and reference specific work in your message. Use our how to email a Japanese professor guide for the proven email structure.
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External profiles
- ORCID: https://orcid.org/0000-0002-6317-9867
- OpenAlex: openalex.org
Profile compiled from public sources (Researchmap, OpenAlex, The University of Tokyo faculty directory). Last refreshed 2026-05. Report incorrect information.