Research summary
A genome-wide association meta-analysis of 20,183 ADHD cases and 35,191 controls identified 12 independent loci surpassing genome-wide significance for attention deficit/hyperactivity disorder, with associations enriched in evolutionarily constrained regions, loss-of-function-intolerant genes, and brain regulatory marks [1]. A schizophrenia GWAS of 11,260 cases and 24,542 controls combined with prior data identified 50 novel and 145 total loci, with fine-mapping plus brain-expression and chromosome-conformation data prioritizing causal genes in 33 loci and demonstrating enrichment in mutation-intolerant genes and regions under strong background selection [2]. A meta-analysis of four longitudinal cohorts showed that DNA-methylation-age acceleration predicts all-cause mortality in later life independently of chronological age and conventional risk factors [3]. The ENIGMA MDD Working Group analyzed harmonized cortical thickness and surface-area estimates from T1-weighted MRI in 2,148 MDD patients and 7,957 healthy controls across 20 sites, identifying consistent cortical alterations [4]; a parallel meta-analysis of subcortical shape in 1,781 MDD patients and 2,953 controls used localized thickness and surface-area metrics across seven bilateral structures to map MDD-related differences beyond volume [5]. The Di@bet.es study, a Spanish national cross-sectional cluster-sample survey of 5,072 participants in 100 clusters with a 55.8% participation rate, used clinical and lifestyle surveys, physical examination, and 75 g OGTT to establish the first national estimates of diabetes and impaired glucose regulation prevalence [6].
Recent publications
- Common SNPs explain a large proportion of the heritability for human heightDOI
- Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorderDOI
- Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol useDOI
- Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traitsDOI
- Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selectionDOI
- DNA methylation age of blood predicts all-cause mortality in later lifeDOI
- Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working GroupDOI
- Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working groupDOI
- A mega-analysis of genome-wide association studies for major depressive disorderDOI
- Prevalence of diabetes mellitus and impaired glucose regulation in Spain: the Di@bet.es StudyDOI
The lab page does not clearly state student acceptance status. Email the professor directly to confirm.
How to apply
Email Nicholas G. Martin 6-12 months before your application deadline. Read several recent papers and reference specific work in your message. Use our how to email a Japanese professor guide for the proven email structure.
For applications via MEXT scholarship: see our MEXT 2027 complete guide and university-specific University Recommendation track.
External profiles
- ORCID: https://orcid.org/0000-0003-4069-8020
- OpenAlex: openalex.org
Profile compiled from public sources (Researchmap, OpenAlex, The University of Tokyo faculty directory). Last refreshed 2026-05. Report incorrect information.